Our body daily produces and receives with food at least 200 g of succinic acid and uses it for normal metabolism and energy supply to cells. However, in many pathological conditions and diseases, this acid is taken in the form of drugs and dietary supplements. Can succinic acid be harmful in such cases?
Extraordinary ordinary succinic acid
Not all organic carboxylic acids are of such interest to biochemists and physicians as 1,4-butanedioic or succinic acid synthesized by the mitochondria of cells - an intermediate product of the Krebs cycle, a substrate and a catalyst for biological processes in the body, including ATP synthesis, redox reactions, acid basic homeostasis, etc.
Numerous reviews of doctors - cardiologists, endocrinologists, neurologists, immunologists - testify in favor of succinic acid (succinate), which has a huge potential and a spectrum of therapeutic effects: antioxidant, antihypoxic, anti-inflammatory, neuroprotective, anxiolytic, restorative.
Experiments have shown that succinic acid helps to reduce fatigue, increases work capacity, physical endurance and mental abilities, and accelerates recovery from serious illnesses and operations.
Other beneficial features succinic acid, read this article.
What is the harm of succinic acid?
But, as you know, there are no absolutely harmless drugs. However, 40 years ago, the US Food and Drug Administration's Special Committee on Substance Safety (SCOGS) stated: “There is no evidence that succinic acid is hazardous to humans or animals. In addition, the animals on which the experiments were carried out tolerate succinic acid in sufficiently large doses. However, a reasonable average daily intake of succinic acid added to food should not exceed 0.01 mg per kilogram of body weight per day. This is an order of magnitude less than the amount of succinate causing toxic symptoms in experimental animals ".
Since there were toxic symptoms, it means that the harm of succinic acid could be manifested in them? And in experimental animals, according to the reports of the researchers, there were gastrointestinal bleeding, diarrhea, lethargy, weight loss; damage to the eyes; erythema and swelling of the skin - here is the harm of succinic acid for the skin (after all, this is how most simple mono- and dicarboxylic acids manifest themselves).
Indian biologists gave this acid to rats, and in 36% of rodents after a month in bladder stones formed. And the results of a study of the effect of succinic acid on the mucous membrane of the colon in rats were published in The Journal of Gastroenterology. It turned out that the higher the level of succinic acid in the body, the more intensive was the formation of erosion of the mucous membrane of the large intestine. It has been suggested that mucosal damage is caused by decreased blood flow and mucosal infiltration by polymorphonuclear cells that generate superoxide radicals. As a result, reactive oxygen species led to the development of oxidative stress and cell apoptosis.
Succinic acid is a food additive, but very biologically active
However, back to people. The FDA (2004) lists succinic acid as a food additive (E363) that regulates acidity food products and allowed for direct addition to them, if the amount of the substance does not exceed the reasonably necessary volumes (6 g per kilogram of product).
Endogenous succinic acid is one of the main catalysts for the degradation of the inhibitory neurotransmitter GABA; therefore, acting as an exogenous component, it can lead to increased psychomotor agitation. In this case, the harm of succinic acid is obvious for children to whom parents give it with good intentions, but without a doctor's recommendation. Succinate behaves actively and is able to provoke not only insomnia, dizziness, fever and urine output, but also damage to tooth enamel, increased acidity of gastric juice (and, therefore, damage to its mucous membrane); muscle and joint pain; liver, kidney and bladder problems.
Pay attention to the list of contraindications for drugs that contain succinic acid as the main active ingredient. This is gastritis with high acidity and gastric ulcer (and duodenum); urolithiasis; Ischemic heart disease; functional kidney failure, etc.
Succinic acid is not transformed into metabolites in the liver: its molecules are partially incorporated between the molecules of phospholipid cell membranes. Also, the ability of succinic acid to local interstitial (extracellular) accumulation in damaged and ischemic tissues of the liver, kidneys, brain, as well as in blood plasma was revealed.
Several years ago, the metabolic succinate receptor GPR91 was classified, which is expressed in the kidney and binds succinate as a ligand. This can lead to the release of renin by the glomerular apparatus of the renal effector cells and the activation of the renin-angiotensin system. This is how succinic acid-induced hypertension develops.
And the accumulation of succinic acid and its compounds in the liver parenchyma (also having GPR91 receptors) is fraught with proliferation connective tissue, that is, fibrosis.
Succinic acid (sodium succinate, butanedioic acid) is a key biochemical molecule. Nature uses it for energy metabolism in plants, human and animal tissues. For centuries, it has been used as an analgesic and natural antibiotic.
Succinates are natural regulators of body processes. The need for them arises with increased stress: both physical and emotional. Acid is unique in that it accumulates only in those areas that need it, bypassing healthy cells and tissues.
It can be purchased in pill form from pharmacies. It is a colorless crystalline solid and is a product of amber processing. Why is succinic acid useful and how important is it for the human body?
Amber is an antioxidant that can help with heart rhythm disturbances, it improves blood flow and urinary tract function.
It is a proven fact that succinic acid has a positive effect on the restoration of the nervous and immune systems, increases the body's resistance to infections, and also helps compensate for energy loss in the body and brain, increasing attention, concentration and reflexes and reducing stress.
The use of succinic acid prevents the development of neoplasms, reduces sugar and neutralizes kidney stones. With varicose veins, butanedioic acid eliminates inflammation, restores blood circulation, and as a result, veins are restored.
Succinic acid is one of the natural acids found in foods such as broccoli, rhubarb, sugar beets, unripe gooseberries and grapes, fresh meat extracts, various cheeses and sauerkraut.
All of these products have very distinct and noticeable flavors, which may in part be due to the enhancement of taste by small amounts of naturally occurring succinic acid.
Succinic acid is an acidity regulator and also a flavoring agent. She can be present in sweets bakery products etc. In addition, it is present in oysters, hard cheeses, yoghurts, sunflower seeds, strawberries, wine, hawthorn, nettle.
The required amount of acid for an adult is 200 mg per day. And if a person does not eat enough food with acid, then he needs to use it as an additive to food.
Indications for use
The use of succinic acid should be agreed with the attending physician. Generally indications are:
- chronic stress conditions in humans;
- heart disease and other diseases of the cardiovascular system;
- anemia;
- radiculitis;
- diseases of the reproductive system;
- allergy;
- asthma;
- SARS, flu, colds (complex forms) - including in children, pregnant women;
- acute bronchitis;
- fibroids, tumors (prevention of development);
- oncological diseases as an antitoxic agent;
- hangover, alcoholism;
- taking vitamins, drugs to reduce their toxic effects;
- taking food supplements;
- prevention of diseases in the elderly.
This substance is considered harmless, but, despite this, you should not self-medicate. Before you start taking it, you need to consult your doctor. A specialist may prescribe a course of tablets or a solution. It is usually recommended to start with 500 mg in the morning with plenty of water.
As soon as the effect is noticeable, the daily dose can be reduced to 200 mg per day. If there is no improvement, then the dose must be increased, but also after consultation with the attending physician.
Excessive use of succinic acid can harm health, and not improve it, therefore it is recommended to be monitored by a doctor. And read the instructions for use.
Succinic acid: contraindications
In some people, this substance can cause severe heartburn or irritate the walls of the stomach, in addition, the drug not recommended for people who have been diagnosed with:
- ulcers gastrointestinal tract(the substance can lead to an increase in the secretion of gastric juice);
- hypertension, glaucoma, ischemic heart muscle disease (the drug can increase blood pressure);
- individual intolerance, allergy to drugs.
Weightloss remedy
In bodybuilding, and as a weight loss aid, sodium succinate is the number one helper. Acid normalizes the functions of organs, has a beneficial effect on the entire body, and he, in turn, fights overweight. People not only lose weight, but are also treated during the intake process.
It improves metabolism, cleanses the body of toxins and waste products at the cellular level. This increases the level of oxygen and energy in the cells; increases resistance to stress, increases the body's resistance to stress and reduces fatigue during physical exercise.
The duration of the course is agreed with the doctor.
Succinic acid in oncology
In Moscow, at the Institute of Biophysics, studies were conducted with the participation of volunteers: in addition to consuming acid, the subjects followed a diet, consumed herbs, complexes of vitamins and minerals, and medicinal drinks. The results were processed over several years.
It was found that the use of succinic acid stops the growth of tumors, and different ones: cancer of the ovaries, mammary glands, cervix, colon.
With the use of standard methods of treatment - surgery, chemotherapy, radiation, and additionally acid - the chances of a cure increase by 2-3 times. It also helps to relieve conditions associated with toxicosis after chemotherapy.
This substance helps to cope with acne, normalizes cells, stimulates and activates metabolism, removes toxins, restores elasticity and freshness of the skin, complexion. Improves the nutrition of skin cells, reduces scars, bags under the eyes, reduces wrinkles.
Grind 2 tablets of succinic acid, pour the resulting powder with 1 spoon of water, mix. Apply to face (avoiding eyes), do not rinse, the mixture should be completely absorbed. Repeat every week.
In addition, succinate peels are popular in cosmetology. They are indicated for people whose skin is prone to acne, sensitivity and rosacea. Peeling strengthens blood vessels and restores blood microcirculation.
The frequency of the procedure depends on the type of skin. It can be done in a beauty parlor, or you can do it yourself. This remedy is effective in fighting cellulite, it helps to smooth out skin texture and reduces stretch marks.
The succinate molecules are injected subcutaneously, which makes it possible to act on the problem locally.
It enhances metabolic processes in cells. Injection administration is the most effective, as it affects the deep layers of the skin. It is used in combination with hyaluronic acid to activate cell metabolism.
Interaction with other drugs
The compatibility of sodium succinate with other drugs has been proven. It can be taken with many medications, but it reduces the effects of barbiturates and anxiolytics.
Application during pregnancy
During pregnancy, the body experiences strong stress, and here butanedioic acid will be a helper and savior. It helps to increase the oxygen metabolism of the body and provides nutrients unborn child. Reduces predisposition to stress and anxiety.
Accelerates the elimination of toxins and toxins from the body. Reduces the risk of anemia. Use during pregnancy and lactation is recommended by doctors in small doses, not more than 250 mg per day.
Before use, a consultation with a treating specialist is required.
Taking the tablets internally helps to improve the structure of the hair, its condition, accelerates growth and prevents hair loss.
In addition, you can supplement the use of tablets for external use. You can add the crushed product to the rinse balm. Or apply to the hair, after shampooing, pre-dissolve 3-4 tablets. You can also add the product to your shampoo.
It is recommended to mix crushed tablets with olive oil, apply to clean hair, hold for 10-15 minutes as a mask, covering your head with a towel, then rinse. You can do this once a week until your hair looks healthy, radiant and no longer shedding.
Succinic acid is a unique agent that is used both in medicine and cosmetology, it helps to fight serious diseases, has a preventive power, and has an effect on various body functions: both physical and psycho-emotional.
But it is always necessary to remember that acid, like any remedy, may have contraindications, therefore, it is recommended to consult a doctor before taking succinate.
succinic acid
Good afternoon, my dear readers! Amber is a beautiful solid resin that simply mesmerizes with its beauty.
From time immemorial, jewelry has been produced from amber, beads and rings are decorated with these stones, but few people know about medicinal properties of this product, and yet our ancestors, starting from the 17th century, used amber powder to treat many ailments.
Today, succinic acid (YAC), namely, it has a beneficial effect on our body, is produced in the form of ordinary tablets and powder, the features and medicinal properties of which we will talk about right now.
Succinic acid: benefits
As a rule, in an ordinary environment familiar to all of us, people do not experience any serious need for succinic acid and its additional intake.
However, it turns out that this product is often simply necessary for a person, in particular for the prevention and elimination of certain diseases.
So, daily intake with meals in the morning and in the evening for a YaK tablet:
1. It has a good effect on liver and kidney function.
2. Increases the body's resistance to external influences and all kinds of harmful toxins.
3. Saturates the body itself and each of its cells with oxygen.
4. Improves the work of the heart muscles and the heart itself.
6. Reduces fatigue during mental, psycho-emotional and physical exertion.
7. Improves metabolism, improves the process of burning harmful fats.
8. Rejuvenates the cells and tissues of the organism and all its systems.
9. Maintains the amount of water and salt in the body at the required level.
10. Helps withstand unstable adverse environmental conditions of life.
11. Treats colds.
12. Helps to cope with diseases of the circulatory system, normalizes the process of blood circulation through the vessels.
13. Eases pain with, helps to eliminate this ailment.
15. It slows down several times the aging process of the skin, reduces the visible changes that occur with age.
16. Quickly restores the loss of strength, eliminates constant drowsiness, raises vitality.
Succinic acid for women Succinic acid: benefits for women
I would like to pay special attention to the benefits of succinic acid for the body of the fairer sex.
2. During pregnancy, taking this remedy, as practice shows, relieves the symptoms of toxicosis and eliminates the unpleasant consequences that occur with hormonal disruption and hormonal changes.
3. During the planning period of a child, amber resin is a kind of positive stimulant of conception, it increases the reproductive function of the body.
4. A weak female body during pregnancy, the named product strengthens and nourishes, helps other useful substances that are ingested with food to be quickly and easily absorbed.
5. Due to the consumption of succinic acid by pregnant women, the fetus in the womb receives the right amount oxygen, which means that the risks of some pathologies and complications during development are reduced to almost a minimum.
Succinic acid: benefits for men
The acid has a beneficial effect on male reproductive function, increases arousal and allows the strong half to quickly recover after intense sports or some serious mental and strength stress.
Succinic acid: instructions for use
Succinic acid, indications for use for weight loss
It only enhances metabolic processes in the human body, which in turn contributes to faster fat burning and weight loss. At the same time, it is very important, along with taking the specified substance, to eat right and devote some time to sports.
How to take succinic acid for weight loss?
To reduce weight, you can use both an aqueous solution of acid and tablets, which you can buy at any pharmacy. In this case, it is important to adhere to the following one of the following weight loss courses:
1. Daily intake of tablets three times a day before main meals for 14 days, after which a break for a week and repeat the course again;
2. Daily intake of the drug 30 minutes before meals 3 times a day according to the system of 3 days of intake - a day of rest, etc.
3. As for the solution, it is used according to the same courses, only instead of taking three times a day, it is drunk once on an empty stomach.
How to take succinic acid for a hangover?
Able to cure succinic acid and hangover syndrome, as strange as it may sound, and quickly enough. To this end, the remedy should be taken on a pill one hour before the morning meal and then the same portion a couple of hours after the meal.
If this does not help, then it is allowed to take an acid tablet every hour, after the second portion, but no more than six tablets per day.
If you need to get rid of your morning hangover as quickly as possible, folk medicine men advise you to drink four tablets of acid on an empty stomach and then another tablet about 2.5 hours after the first meal.
Succinic acid in bodybuilding How to take succinic acid in bodybuilding?
Athletes and bodybuilders are prescribed 500 mg of succinic acid. at one time before lunch (until 12 o'clock). Seeing positive changes in the body, the indicated dose should be gradually reduced to 100 mg. in one go.
In this case, 100 mg. can be divided into several doses per day and it is best to drink the remedy before meals for 30-40 minutes.
Attention! At high daily doses of succinic acid consumption, the course of administration should not exceed 10 days. A smaller dose is best taken according to the system of 3 days of intake, 2 days of rest from the prophylactic agent.
Succinic acid for colds, how to take?
During the season of respiratory viral infections, for prevention, it is recommended to eat an egg pill three times a day.
With the initial, newly emerging symptoms, indicating a cold, in order to relieve them, the named dose must be doubled and taken until the problems are eliminated.
The use of succinic acid in medicine
In medicine, succinic acid is used as a pure product in the form of tablets (0.1 grams of active ingredient per tablet) and powder (the amount of active ingredient depends on the volume of the package), and the substance on the basis of which it is made aqueous solutions and some other medications.
The standard course of admission is 1 gr. powder or 1 tablet of egg per day for a month. This course is recommended for the normalization of the functions of the internal organs of a person, for the general strengthening of the body and improvement of well-being.
If there is no positive result, then the daily dose should be doubled. Moreover, it should be divided into three parts and taken during the day at regular intervals.
Important! It is necessary to take a break for a day every three days. This will avoid drug overdose!
Succinic acid: method of administration and dosage
1. In oncological diseases, acid is taken as an additional component to the main treatment. The daily dose of taking YaK is 5-10 tablets, which depends on the general condition of the patient. In the most severe cases, the dose may rise to 20 tablets per day.
Important! For better assimilation of the drug by the body, it is recommended to take YaK together with freshly squeezed juices from berries and fruits.
2. To facilitate the general well-being of patients with ischemic disease heart and atherosclerosis of the vessels of the lower extremities, UC is prescribed after meals, one tablet 2 times a day. Such a course allows patients to reduce swelling and pressure surges, to reduce the frequency of angina attacks and shortness of breath.
3. To improve the state of blood vessels in patients with deforming osteoarthritis, obliterating atherosclerosis, osteochondrosis, chronic venous insufficiency, it is recommended to take UC 2 times a day, 1 tablet, as an addition to the main treatment.
Treatment with succinic acid in old age
1. Succinic acid is used to treat the elderly. In elderly people, after 60 years, it is known that metabolism and energy production in cells slows down, which worsens the general functioning of organs and dystrophic changes in them.
The acid allows you to slow down the aging changes in the body and maintains the functioning of all body tissues at a good level. Yak speeds up metabolism, activates energy production, which means it improves the quality of life and its duration.
2. Due to this "rejuvenating" effect, it is recommended to take YaK to all people over 55 years of age. The course is 1-2 months, 1 tablet a day after a meal. This will strengthen the immune system and slow down the aging process.
Succinic acid in cosmetology
Succinic acid is widely used today for the production of cosmetics. In particular, a huge number of skin rejuvenating creams, scrubs, masks, firming lotions, balms and shampoos are made on its basis.
Succinic acid for hair: application
In order to improve the structure of the hair, to give it special strength, strength, it is necessary to dilute the powder of succinic acid with water to get a kind of paste, and apply this paste to the scalp along the entire length of the hair, and from their very roots.
This simple procedure should be repeated once a week and continuously for a whole month. The result, you can be sure, will not keep you waiting.
How to take succinic acid for skin rejuvenation?
To rejuvenate the skin of the face, grind 2 tablets of the product, add the same amount of mummy, dilute with ten milliliters of almond or classic olive oil.
Apply the finished mask to the face with massage movements daily before bedtime, after which, after holding the composition for half an hour, rinse it off with water.
Attention! Before applying the anti-aging mask to the skin of the face, remove all daytime makeup plus the excess fat released by the skin during the day with a cotton swab.
Video: Succinic acid: peeling and face mask
What foods contain succinic acid?
By including these products in your daily menu, you can completely enrich the body with the missing amount of acid extracted from the amber resin and no longer consume this agent in tablets.
The acid contains:
- in bread made from rye flour, in rye bread crumbs;
- with individual intolerance to the specified component;
- with angina pectoris;
- with eye diseases (retinal degeneration, etc.);
- with urolithiasis;
- with an ulcer, and especially during periods of its exacerbation;
- with hypertension.
Among other things, it is best not to consume succinic acid immediately before bedtime, this can lead to insomnia.
Helpful advice! No matter how you and for what purpose do not use succinic acid, consult your doctor before consuming it, he will help you correctly adjust the dose and prescribe a timely course of treatment or administration.
Video: Succinic acid - benefits
In contact with
Description up to date on 04.06.2015- Latin name: Succinic acid
- ATX code: V81BF
- Active substance: Succinic acid
- Manufacturer: Elite-Pharm LLC, Ukraine Marbiopharm OJSC, Russia
Composition
The composition of Mosbiopharm succinic acid tablets contains 100 mg of succinic acid, as well as potato starch, sugar, calcium stearate, talc, aerosil.
The tablets produced by the Elite-Pharm company contain 150 mg of succinic and 10 mg of ascorbic acid.
Release form
The supplement is available in tablets of 0.1 and 0.25 g in packages No. 40, No. 80 and No. 100 tablets in a package.
pharmachologic effect
Antihypoxic, metabolic, antioxidant .
Pharmacodynamics and pharmacokinetics
Succinic acid (YA) is intracellular metabolite of the citrate cycle (Krebs cycle). In the cells of the body, it performs a universal energy synthesis function .
With the participation of the coenzyme FAD (flavin adenine dinucleotide) and under the influence of succinate dehydrogenase (a mitochondrial enzyme of the oxidoreductase class), it is rapidly biotransformed into fumaric acid and further into other metabolic products of the Krebs cycle (the end products of the UC metabolism are carbon dioxide and water).
Stimulates the breakdown of glucose through the aerobic pathway and the synthesis of ATP, which plays an important role in the energy metabolism in the body; improves tissue respiration by activating electron transport in mitochondria.
The substance has strong antioxidant properties directed mitochondrial action, which contributes to the rejuvenation of the body at the cellular level.
Widespread use in medicine is due to the ability to stimulate the compensatory-protective and adaptive capabilities of the body; increase the formation of hydrochloric acid and the secretory function of the stomach glands, improve appetite and contractile function of smooth and striated muscles, increase diastolic blood pressure and physical performance.
In addition, by activating intracellular metabolism and cellular respiration, UC promotes the elimination of toxic substances from the body and reduces the toxic effect of alcohol.
When ingested, YaK penetrates from the digestive tract into tissues and blood, takes part in catabolic reactions and after half an hour is completely degraded to the end products of metabolism. The substance does not accumulate in the body. T1 / 2 - about 26 minutes.
Indications for use: what are succinic acid tablets from?
The use of succinic acid in tablets is shown as a dietary supplement - a source of succinic acid.
The agent is prescribed for functional asthenic conditions ... Its effect is especially strong in case of age-related ailments and in extreme conditions (including in conditions of oxygen starvation).
Succinic acid (UC) preparations help to reduce the manifestations of sclerotic changes (forgetfulness, increased fatigue, etc.) and effectively relieve headache, the cause of which is a malnutrition of brain cells.
These properties of the YaK make it advisable to use it for ischemic conditions , muscle contractures (muscle stiffness), vascular spasms.
Doctors recommend administering UC preparations as an addition to the main therapy for diseases of the heart and blood vessels. Indications for the use of the supplement include: atherosclerotic vascular lesions lower limbs, .
With all these diseases, the patient is forced to take a large number of drugs for a long time (sometimes for life): anti-sclerotic, hypotensive, anticoagulant, vasodilator, potassium-containing, maintaining cholesterol balance, diuretic.
The introduction of UC into the treatment regimen can significantly reduce both the number of drugs taken and the duration of their administration. The effect is achieved due to the pharmacological properties of UC and due to its ability to enhance the effectiveness of drugs of the main therapy.
Application of YaK at a dose of up to 1 g / day. provides a distinct potassium-retaining and diuretic effect, which contributes to an increase in daily urine output and a rapid decrease in edema in patients with various diseases circulatory system ( rheumatic vices , Ischemic heart disease etc.), and also allows you to significantly reduce the dose cardiac glycosides and diuretics .
The research results are confirmed by the dynamics of the ECG. In all patients who took part in the experiment, after a course of administration of UC preparations, blood circulation improved in coronary vessels , heart rate normalized, blood levels of PTI decreased and in the blood and the fraction returned to normal β-lipoproteins .
A positive effect is also observed in the case of the use of UC drugs in combination with drugs for treatment discirculatory encephalopathy and cerebral atherosclerosis .
Moreover, it becomes noticeable after 3-5 days, and after 2-2.5 months in patients, the manifestations of sclerotic symptoms significantly decrease: dizziness decreases, as well as the intensity and frequency of headaches; improves memory, mood and sleep; concentration of attention increases.
With diseases of the musculoskeletal system (for example, with deforming or ) in patients taking UC, pain, swelling and deformation of the joints decreases, their mobility increases, and, in addition, the concentration of uric acid in the blood decreases.
Studies on the use of the supplement in patients with bronchopulmonary pathologies showed that prescribing to a patient from 0.5 to 1.5 g of UC per day improves overall well-being and prolongs the period of remission. Changes are also noted in the indicators of the state of the immune status, both in the cellular and in the humoral link.
The prophylactic use of UC preparations in a 2-3-week course during periods of seasonal exacerbations of chronic diseases makes it possible to achieve that even if the patient does get sick, the disease proceeds in a milder form, and recovery occurs much faster.
Taking high doses of UC during acute respiratory viral infections and influenza prevents the development of the disease and allows you to restore your ability to work within a few days.
Succinates regulate production , which helps to restore the metabolism of saccharides. This property allows the use of UC for prevention and treatment. non-insulin dependent diabetes .
Increased secretion insulin due to the fact that UC activates enzymes that do not depend on the level of dextrose in the body.
UC prevents genetic disorders that result from the influence of carcinogenic substances and lead to uncontrolled cell division. The use of supplements with succinates allows several times to reduce the mortality rate of cancer patients and improve their quality of life.
It has been experimentally proven that succinates inhibit the growth of neoplasms. By accumulating mainly at the site of tumor formation, UC prevents proliferation malignant cells .
In addition, the drug helps to reduce the severity side effects chemotherapy: loss of energy, depression, nausea.
The positive effect of the use of YaK is most pronounced when , , cysts and others benign tumors .
Special attention should be paid to the use of YaK in gerontological patients , which in the overwhelming case have a complex pathology.
The benefit for the body of an elderly person is that taking YaK tablets can reduce the severity of symptoms of age-related diseases and at the same time reduce the amount and dose of pharmacological drugs they need.
The greatest efficiency is observed when using YaK in combination and with means that restore intestinal microflora ... This combination helps to increase immune status , while in patients there is a clear tendency to normalization of the serum concentration of malondialdehyde and the severity of endogenous intoxication decreases.
For preventive purposes, egg can also be taken by healthy people. The introduction of the supplement into the diet of athletes makes it easier to adapt to constantly increasing loads and relieve muscle pain after intense training.
Also, the remedy is used for intoxication of various etiologies (including alcoholic and drug).
Contraindications to succinic acid
Succinates are natural for human body substances, therefore, even with prolonged use, they do not cause side effects and dependencies.
However, UC drugs have contraindications. Tablets are not prescribed for:
- during the period of its exacerbation (succinates strongly irritate the mucous membrane of the digestive tract);
- gastritis with hypersecretion ;
- high blood pressure ;
- urolithiasis (UC stimulates metabolism, which leads to more intense formation of oxalate calculi);
- severe preeclampsia in pregnant women ;
Yak excites the brain (the drug has the opposite effect of tranquilizers and glycine), so you should not take pills at night.
Side effects
Hypersensitivity reactions gastralgia , hypersecretion of gastric juice ... Those prone to arterial hypertension people against the background of the systematic use of UC drugs is possible increase in blood pressure .
Succinic acid tablets: instructions for use
In accordance with the instructions for use, Succinic acid is taken before meals, previously dissolved in fruit / berry juice or mineral water.
The daily dose for an adult is 0.5-3 tablets. The duration of the course is 4 weeks.
During pregnancy, the dose depends on the duration. For a period of 12-14 weeks, pregnant women are prescribed to take the supplement at 0.25 g per day for a ten-day course. In the second trimester, it is advisable to drink the drug between 24 and 26 weeks, in the third - about 10-25 days before delivery. During the entire period of pregnancy, it is allowed to take no more than 7.5 grams of egg.
For the prevention of poisoning with alcohol decomposition products, it is recommended to take 0.25 g of YaK half an hour or an hour before drinking alcohol. With alcohol withdrawal, treatment continues for 4 to 10 days. The daily dose is 0.75-1 g of egg, divided into 3-4 doses. The supplement can be taken either alone or in combination with other pharmacological agents.
To improve appetite, it is shown to take 0.25 g of egg from 1 to 3 times a day, before meals. If taking the supplement is accompanied by a feeling of heaviness in the epigastric region, the tablets are taken after meals. The duration of the course is from 3 to 5 days.
As an irritant to the gastric glands, before the study of the secretory capacity of the stomach, YaK is taken on an empty stomach, 1 tablet, after dissolving it in a dessert or a tablespoon of water. The study is carried out at standard time intervals using generally accepted methods of analysis.
Cancer patients for prophylactic purposes, a daily intake of 2-3 tablets of 0.1 g is shown. If necessary, the dose is increased to 5-10, and in especially severe cases - up to 20 tablets per day.
During periods of exacerbation of seasonal diseases of UC, for prophylaxis, 0.5 g is taken twice a day for a course of 2-3 weeks. With influenza and ARVI at the initial stages of the development of the disease, tablets are taken 1 or 2 times a day, 3-4 pieces per dose. With hyperthermia, UC should be drunk in combination with .
The use of YaK in cosmetology allows you to slow down the aging of the skin, cleanse it at the cellular level and whiten it, remove scars, acne and swelling, remove toxins and saturate it with oxygen.
For the skin of the face, neck, décolleté and skin around the eyes, use in serums, masks, lotions, creams, peels. Cosmetics with the addition of YaK are used in almost all anti-aging programs.
To prepare a cream with YaK, it is enough to add a tablet dissolved in a teaspoon of flower water to 20 ml of a cream suitable for the type of skin. To completely dissolve the tablet, it is left in water for several hours.
To make a mask, you should simply apply to the skin crushed into powder and mixed with flower water to the consistency of thick sour cream, YAK tablets. After 15-20 minutes, the mixture is washed off and the cream is applied to the skin. For women with dry skin, the procedure can be repeated no more than once a week, if oily skin the mask is allowed to be done three times a week.
To prepare the tonic, mix the following components: fragrant water (50 ml), 10 drops each of ylang-ylang and rosemary oils, 2 powdered YaK tablets, benzyl alcohol (0.5 ml). Alcohol acts as a preservative. If the tonic will be stored for a short time (no more than 7 days) and in the refrigerator, you do not need to add it.
To make scars and stretch marks less noticeable, you should prepare a thick mixture of flower water and yak, apply it to the problem area and massage for 1-2 minutes. After 15 minutes, you can rinse off the remaining peeling mass and apply cream or milk to the skin.
A mask with a mummy is no less useful for stretch marks. For its preparation, a few tablets and a few YaK tablets are dissolved in a little olive or almond oil. When the mass becomes homogeneous, it is applied to problem areas and the skin is thoroughly massaged. After an hour, the mask is washed off with cool water.
The result is noticeable with systematic use. It is considered optimal to do the procedures daily for 3 weeks, then withstand a break and, if necessary, repeat the course.
The use of YAK for hair enhances blood flow to the scalp, strengthens the hair, makes it more hydrated, shiny and manageable.
The product can be added to regular shampoos and masks, or it can be rubbed into the scalp after soaking in a small amount of water / hydrolat. After applying the gruel to the hair, wrap the head with a towel for 2 hours (you can leave the mask longer). The procedures are repeated daily for a month.
Overdose
An overdose of succinic acid is impossible.
Interaction
Succinic acid is compatible with most pharmacological agents. The exception is anxiolytics and barbiturates (succinates reduce their effectiveness).
Can be used as an adjuvant in complex therapy infectious diseases to reduce the toxic effects of other drugs, including antibiotics , antihelminthic, anti-tuberculosis and anti-inflammatory drugs .
Terms of sale
The product is sold without a prescription.
Storage conditions
Store the drug out of the reach of children, protected from moisture at temperatures up to 25 ° C.
Shelf life
The tablets are suitable for use within 4 years after the date of issue.
special instructions
What is succinic acid and what does the body need succinates for?
Succinic or butanedionic acid is a dibasic carboxylic acid that has the appearance of colorless crystals and is readily soluble in alcohol and water.
In small amounts, this organic compound is found in some vegetables and fruits, but its main source for medicine, food and chemical industries is natural amber.
The chemical formula of the substance is HOOS-CH2-CH2-COOH.
According to Wikipedia, succinate is involved in tissue respiration of oxygen-breathing organisms.
The benefits and harms of succinic acid
The most valuable properties of YaK are its ability to facilitate the adaptation of the body to stressful situations and protect it from various kinds of toxic poisoning.
This makes it possible to effectively use the supplement as an adjunct to the main therapy for a fairly wide range of diseases.
However, if used uncontrolled, the egg can harm the body. The tool has a number of contraindications and is not intended for systematic daily intake. As a rule, the supplement is drunk for no more than 4 weeks.
The use of succinic acid in crop production
For plants, succinic acid is an antistress and growth stimulant.
The use of succinic acid for plants is possible in several ways. For seedlings, spraying of all parts of the plant (roots, leaves, stems) is shown, as well as soaking the roots for 0.5-4 hours before planting (after soaking, the roots are dried for half an hour, and then the plants are planted in the ground).
For flowers, the solution is a means intensive care: it is watered with the roots of the plant and the aerial parts of the plant are sprayed with it.
In case of problems with tops turgor for flowers (and, in particular, for orchids), a solution of succinic acid with glucose, niacin and vitamin B1 is used (1 tablet of each component per 1 liter of water).
To prepare a solution for irrigation, 1-2 tablets (sometimes 4) are poured with a liter hot water, and then cooled. For indoor plants, treatment with such a "medicine" should be carried out no more than once a month.
Analogs
Amber antitox , Succinic acid-Elit-farm , Complex "Inosine + Nicotinamide + Riboflavin + Succinic acid" , Amber , Mitomin , Yantavit , Brewer's yeast with succinic acid .
Succinic acid and alcohol
The alcohol consumed in the liver is very quickly converted to acetaldehyde. The intake of succinic acid accelerates the breakdown of acetaldehyde into substances less harmful to the body, accelerates detoxification and improves overall well-being.
The supplement can be taken:
- before drinking alcohol;
- with a hangover syndrome;
- for treatment alcohol withdrawal .
As part of complex therapy, it is possible to use it for alcoholism. Course use for several months is allowed only as directed by a doctor and only after the patient undergoes a comprehensive examination.
The use of succinic acid for a hangover
Many toxicologists tend to consider succinic acid as the # 1 hangover remedy. Acting on the tricarboxylic acid cycle, which is a key link in energy metabolism, succinate stimulates it in accordance with the principle of mobile balance and promotes the elimination of under-oxidized metabolic products.
If drinking alcohol was accompanied by a plentiful snack, it is recommended to supplement the use of YaK with an enema.
To prevent a hangover, 2 tablets of the supplement should be taken about an hour before the planned meal. The action develops in half an hour and lasts from 2 to 3 hours.
Succinic acid for weight loss
The positive effect of using succinic acid for weight loss is primarily due to the ability of the substance to cleanse the body of accumulated toxins, activate the function of the digestive system and remove excess water from the body.
Analyzing the reviews of nutritionists about the effectiveness of the remedy, we can conclude that for weight loss it should be used only as an additional stimulator of metabolic processes. Without adjusting your diet and exercise, you will not be able to get rid of subcutaneous fat reserves.
The second option involves taking 1 gram of succinic acid daily for 30 days. The entire dose is taken at one time before breakfast.
Application during pregnancy
The use of succinates during pregnancy can facilitate hormonal changes female body, helps to strengthen immune system , as well as a decrease in the frequency and severity , prevents the loss of strength and complications of pregnancy, helps to compensate for the increased energy expenditure, ensures the creation of an optimal environment for the development of the fetus, in which the latter is sufficiently supplied with nutrients and oxygen.
Yak acid helps to strengthen histohematogenous barrier between the blood and the fetus, which in turn protects the fetus from the effects of pathogens and toxins.
Thus, the risk of having a child with congenital diseases or malformations is significantly reduced.
It is important to remember that during the entire period of pregnancy, it is contraindicated to take more than 7.5 g of egg.
In Europe, the drug "Coenzyme Q10" is very popular, its analogue is succinic acid. Its benefits and harms have been studied extensively, in today's material we will consider them in more detail.
Succinic acid - indications for use
Succinic acid, the benefits and harms of which we are considering, has certain indications. Before taking dietary supplements, read them:
- muscle / vascular spasms that are neurological in nature;
- vegetative-vascular dystonia;
- pathologies associated with poor enrichment of brain cells with oxygen;
- lingering migraines, headache;
- deterioration of cognitive functions (speech, memory, intelligence, etc.);
- moral fatigue, depression, general weakness and apathy;
- frequent exposure to stress;
- physical plane loads;
- overweight, obesity;
- low immunity;
- atherosclerosis of the vessels of the lower extremities;
- poor elasticity muscle fibers, "Stiffness" / "ossification" of tissues.
This is not the whole list of indications for admission. It all depends on the state of health, so we advise you to visit a doctor, get tested and get approval for an appointment.
The benefits of succinic acid
Succinic acid has both benefits and harms. Now we will analyze the qualities valuable for health, and below we will describe the possible negative aspects.
# 1. For the brain
The main purpose of the dietary supplement is to saturate the cells with oxygen, with which the acid copes well. First of all, the positive effect affects the brain. A person's memory and concentration improve, and his intellect increases. The drug is especially recommended for students and people who work a lot mentally. Amber is also prescribed to persons with diagnosed vegetative-vascular dystonia, accompanied by severe headaches.
# 2. For heart
The drug is prescribed for the treatment of ischemia, prevention of heart attack and increased scarring of tissue, if an attack has already occurred. It is enough to drink a course to normalize the pulse and take the load off the heart muscle.
No. 3. For the liver
The dietary supplement launches the cleansing of the liver from toxic substances, decay products and ethanol (after a violent feast). Usually the drug is drunk with a hangover to relieve unpleasant symptoms. Succinic acid restores the filtering functions of the liver and the structure internal organ generally. This is extremely relevant for individuals who constantly abuse junk food and alcohol.
No. 4. For the prevention of oncology
Succinic acid reduces the likelihood of the formation of malignant tumors, although the benefits and harms in this matter are not fully understood. The substance is added to cancer drugs because it has the ability to block the blood flow to cancer cells and trigger the self-destruction of the formation.
No. 5. To increase the tone of the body
Assign dietary supplements to those who are systematically exposed to negative influences environment, stress, viral infections and other attacks from the outside. Acid increases the defenses, as they say, on all fronts. A person becomes less susceptible to negativity, climate change, seasonal flu epidemics, etc.
No. 6. For the treatment of diabetes
The drug acts on the pancreas, improving its functioning and, as a result, insulin synthesis. This property has a beneficial effect on the health of diabetics. The dietary supplement breaks down and removes excess glucose, lowering blood sugar levels. The disease proceeds more easily, the dependence on the injected insulin decreases.
No. 7. For the prevention of anemia
Anemia refers to a disease that develops against the background of a low level of iron in the blood. This leads to dizziness, apathy, and rapid mental exhaustion. Succinic acid, the benefits and harms of which we are considering, reduces the risk of developing anemia to zero. The drug increases hemoglobin, therefore it is indicated even for pregnant women.
No. 8. To enhance the action of drugs
If a person is undergoing a course of antibiotics or other serious medications, you can drink succinic acid to enhance the effect of medications. It will speed up the entry of drugs into the bloodstream, while at the same time relieving stress on the liver and urinary system.
No. 9. For the circulatory system
Another very important property of dietary supplements is the ability to increase blood microcirculation in blood channels. If a person has poor blood circulation in the extremities, succinic acid will be extremely beneficial. Legs will stop freezing, chilliness and cramps will disappear. Also, acid cleans blood channels from cholesterol plaques, prevents atherosclerosis, varicose veins and other pathologies of this kind.
No. 10. For the genitourinary system
Succinic acid is prescribed for men to treat prostatitis. For all other persons, the benefits and harms are also unequal, valuable properties clearly prevail. Warned urolithiasis disease, sand comes out of the kidneys (for large formations, you need to get advice). It also improves blood flow to the pelvic organs, and prevents many serious diseases.
No. 11. For the nervous system
The instructions for the use of succinic acid indicate that it should be taken in case of disorders of the nervous system. If you are often worried about anxiety, sleep problems, obsessive thoughts and fears, then taking a dietary supplement will be beneficial. Sleep will improve, the psycho-emotional environment will stabilize.
No. 12. To get rid of bad habits
If the goal is to quit smoking, then it is recommended to take a course using the drug. The acid reduces the dependence on nicotine and the withdrawal syndrome itself, due to which the crisis period proceeds smoothly. It's also easy to quit coffee by reducing your caffeine cravings.
No. 13. For general health
It is recommended to drink succinic acid periodically in order to increase the body's resistance to viruses in the off-season, with a change in climate and after an illness. The benefits and harms of dietary supplements for athletes have been studied; in the absence of prohibitions on taking the drug, the drug will only go a plus. It will speed up lactic acid breakdown and post-workout recovery.
How to take succinic acid
1. Succinic acid has instructions for use. An adult is recommended to take 1 tablet twice a day. The dosage can be increased to 3 tablets per day. The course lasts 30 days.
2. When children take succinic acid, the daily dosage is reduced. The child is given 1 tablet 1 time per day. The drug is mixed into food, jelly, compote, water, etc.
3. It is important to remember that it is strictly forbidden to take dietary supplements on an empty stomach. Acid is taken with food or immediately after a meal. If it was not possible to eat, then drink a glass of milk, then take the tablets.
Succinic acid for weight loss
1. Succinic acid is used for weight loss as a means to accelerate metabolic processes. Along with this, the supply of energy to cells is increased. Therefore, the benefits and harms of dietary supplements are obvious.
2. Regular consumption dulls hunger and constricts the stomach. As a result, there is no need to eat large portions of food. Natural weight loss occurs.
3. BAA must be combined with balanced nutrition... Only in this way can you quickly and safely say goodbye to excess weight. Also, the body is cleansed of slagging and toxins.
4. To start losing weight, the first 3 days, acid should be taken twice a day during a meal, 2 tablets. On the 4th day, arrange unloading, do not take dietary supplements and do not load the body physically. Further, the remedy is taken according to the same scheme for 25-30 days.
Important!
Succinic acid is not a medicine specifically designed for weight loss and anti-obesity. Despite the fact that there are instructions for use, you need to balance your diet and start exercising.
Succinic acid during pregnancy
Succinic acid has both benefits and harms. To avoid negative impacts, follow the recommendations.
1. Systematic consumption of a food supplement will help the body of a pregnant girl to improve oxygen metabolism in tissues. This is necessary in order to prevent the development of fetal hypoxia.
2. Acid is especially useful for early dates carrying a baby. The advantage of the drug is that it prevents all the unpleasant consequences of toxicosis.
3. Systematic consumption of dietary supplements during pregnancy allows you to completely cleanse the body of harmful compounds. As a result, a strong immunity begins to form in the baby.
4. Acid acts as a stabilizing agent nervous system... Because of this feature, the baby has a reduced risk of developing ailments of the cardiovascular and nervous systems.
5. During pregnancy, the girl's body is subject to colossal hormonal changes. Acid stabilizes general state and hormonal background. The mood improves.
6. The substance has a positive effect on the activity of the kidneys, because of this, the swelling of the extremities disappears. The body is better cleansed of toxic compounds.
7. Succinic acid, the benefits and harms of which are obvious, should be included in the daily menu. This will avoid the development of anemia.
8. As for the negative side of the drug, it can harm the expectant mother if later dates pregnancy, preeclampsia develops.
The harm of succinic acid
Before taking, consider when the composition will harm:
- high blood pressure;
- an ulcer in the acute stage;
- aggravated urolithiasis;
- late stage preeclampsia;
- glaucoma;
- individual intolerance.
Succinic acid has many positive properties. Its benefits and harms are obvious. In order not to face the negative side of dietary supplements, study the contraindications and observe daily rate... For the treatment of diseases, consult your doctor in advance.
